Thermo Scientific Q Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer
High-resolution, accurate-mass LC-MS for identification and quantification.
The Q Exactive Plus combines a quadrupole mass filter with an Orbitrap mass analyzer. It measures mass with enough accuracy to determine elemental composition, and enough resolution to separate compounds with nearly identical masses.
This instrument is the laboratory’s most powerful analytical tool. It supports both targeted quantification and untargeted screening, where data are collected on everything in the sample and can be searched again later as new questions arise.
Applications
- Identification of unknown compounds by accurate mass and MS/MS
- Targeted quantification of trace-level analytes
- Untargeted metabolomics and chemical profiling
- Screening for contaminants, residues and degradation products
- Characterization of peptides and natural products
Typical Sample Types
Extracts and liquids compatible with LC-MS. Sample preparation is discussed on a project basis.
Key Specifications
| Analyzer | Quadrupole-Orbitrap |
|---|---|
| Resolution | Up to 140,000 FWHM at m/z 200 |
| Mass accuracy | < 3 ppm (external calibration) |
| Mass range | m/z 50–6,000 |
| Ionization | Heated electrospray (HESI) |
Specifications are provided for general reference. Method performance depends on sample matrix and project requirements.
To discuss a project that uses the Thermo Scientific Q Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer, please call (314) 652-3448 or submit a project quote request.
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